n the turbulent business environment, organizations try to develop their agility; therefore, they need to consider business process re-engineering (BPR). The present study is aimed, using the system DYNAMIC approach, at investigating and analyzing the effects of BPR factors on the organizational agility in the PMO which has the biggest container ports in Iran handling the highest volume of container operations and playing a very important and vital role in the country's economy and Trade. PMO also tries to maintain a high level of responsiveness to achieve agility and remain competitive in the global marketplace; therefore, it needs to consider BPR which is operationalized through cultural factors, communications, methodology, project management, strategic alignment, information technology, leadership, empowerment, and performance management. Initially, the literature was reviewed and the gathered data provided us with the possibility to present a conceptual framework for the study. Subsequently, some indices were identified for model variables evaluations through interviews with experts. Effort has been made in this research to simulate successful BPR key factors and organizational agility. Accordingly, first the main system defining variables were identified and realized to a great extent. Then, their relations were codified according to the casual loop diagrams.Next, its technical structure was completed through the main model design according to the stock-flow diagram and was assimilated in the VENSIM software, and some effective parameters were identified through the model execution and analyses of its results. Finally, more effective, principal indexes were determined. Although more detailed studies and model development deem necessary and real world variables need to be added to the model, it can still test and assess any strategy and solution almost satisfactorily.